1. Test the hormone T3 and T4
It is not necessary to reflect the level of thyroxine (T4) and theoverall physiological function as the levels vary depending on thyroxine Concentration of carrier proteins (Thyroxine-Binding Globulin and Prealbumn) and these proteins are affected by situations such as physiological Pregnancy and the pill or other estrogen-containing compounds.
And the level of natural total T4 in the blood ranges from 5-12micrograms / 100 ml (65-156 Nanomul / liters).The natural levels of T3 in the blood ranges were between 0.07-0.17 micrograms / 100 ml blood (0.91 - 2.2 Nanomul / L)
There are cases with high levels of T3 and T4 and the other casesat least all of them and we will both cases as follows:
All cases of high level of T3 and T4 in the blood:
(A) and excessive thyroid function.
(B) the high level of protein in the cradle of thyroxine (Thyroxine - Binding Protein TBG)
(C) Graves disease.
(D) during the active inflammation of the thyroid gland.
(E) the thyroid gland poisoning by T3
All cases the low level of T3 and T4 in the blood:
(A) inadequate thyroid function.
(B) the low level of thyroxine carrier protein.
(C) after partial or total excision of the thyroid gland.
2. Test the free thyroxine (Free T4)
Dependent metabolic activity of the hormone (T4) on the concentration of (T4) free (non-mobile on the protein).
The normal range for this hormone free between 0.8-2.4 ng / 100ml (0.01-0.03 Nanomul / l).
Increase the level of this hormone in the case of hyperthyroidismand thyroid function in the case of her infection is also an active Nand the level goes down in the case of inadequate thyroid function, and useful measurement of thyroxine free to confirm thediagnosis of an overactive thyroid gland when the rise in thyroxinetotal on the upper limits of normal.
Calculating the proportion absorbed on the T3 Resin (Resin T3 uptake - RT3 U)
This account is a measure of the parts is loaded from theglobulin-carrying thyroxine, if added (T3) to the irradiatedpatient's serum, part
It becomes associated with protein and the other part remainsfree, and then absorbs the heat on the shearing (Resin) (is asimilar material is chemically for industrial purposes)
And can be detached from the serum because the ratio of (T3) on the uptake (Resin) is inversely proportional to the free protein carrier.
This ratio ranges between 25-35% normal
We get a high value in the case of hyperthyroidism and thyroid function in cases associated to the low level of globulin-carryingthyroxine also states
Without any change in the function of the thyroid gland.
We note the low value of this ratio in case of failure of thyroid function in cases associated with the high level of globulin-carrying thyroxine
Also without any change in thyroid function.
Measurement of free T4 (Free Thyroxine - FT4I)
This is a measure of the amount of measurement (T4) fromserum free and we get by multiplying the value of (T4) by (T3)absorbed on the Rein (RT3 u)
We get high values in cases of hyperthyroidism and thyroid function, and we get low values in cases of lack of function, regardless of any change
In the level of globulin-carrying thyroxine in the blood.
3. Stimulating hormone of the thyroid gland (TSH) (Thyroid Stimulating Hormone):
This hormone is secreted from the Space anterior pituitary gland(Anterior Pituitary Gland) in the bottom of the brain after the arrival of a signal
Alhaaboethelams (Hypothalamus) (visual subcutaneous bed - in the midbrain) and works of this hormone to stimulate the entry of iodine to the thyroid gland
For the manufacture of hormones T3 and T4 and the purpose ofthis analysis is to determine the location and type of the disease, which affects the thyroid gland.
The rate of natural range in the blood of 0.5-5 ml and IU / liters.
We note the high level of circulating TSH after eradication of the thyroid gland partial, and in cases of failure and the primaryfunction of the thyroid gland which results in disease Alkhozb, as well as in rare cases, such as hyperthyroidism and thyroid function due to a defect in the pituitary gland andAlhaaboethelams.
Overall, the measure hormone (TSH) is useful in the following cases:
- Hereditary hypothyroidism.
- Differentiate between primary hypothyroidism and secondary education.
- Proof of primary hypothyroidism (if symptoms are minimal).
- During testing of the pituitary gland failure for any reason.
التسميات
Thyroid